KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH18A1
All Species:
37.58
Human Site:
S512
Identified Species:
59.05
UniProt:
P54886
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54886
NP_001017423.1
795
87302
S512
G
G
K
E
A
A
H
S
N
R
I
L
H
L
L
Chimpanzee
Pan troglodytes
XP_001155890
796
87730
S513
G
G
K
E
A
A
H
S
N
R
I
L
H
L
L
Rhesus Macaque
Macaca mulatta
XP_001099359
795
87154
S512
G
G
K
E
A
A
H
S
N
R
I
L
H
L
L
Dog
Lupus familis
XP_534976
795
87233
S512
G
G
K
E
A
T
H
S
N
R
I
L
H
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z110
795
87278
S512
G
G
K
E
A
A
H
S
N
R
I
L
H
L
L
Rat
Rattus norvegicus
NP_001101994
795
87311
S512
G
G
K
E
A
M
H
S
N
R
I
L
H
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508419
607
66410
V354
L
V
N
T
R
E
E
V
E
D
L
C
R
L
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086040
815
89190
T532
G
G
K
E
A
S
N
T
N
Q
I
L
Y
R
L
Zebra Danio
Brachydanio rerio
NP_001077015
782
85358
T494
G
G
K
E
A
A
N
T
N
R
I
L
H
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649375
776
84074
S498
G
G
K
E
A
A
H
S
N
K
A
L
M
E
L
Honey Bee
Apis mellifera
XP_396399
732
79216
A472
G
P
V
G
A
A
N
A
I
S
L
I
S
T
R
Nematode Worm
Caenorhab. elegans
P54889
800
86509
S504
G
G
K
E
A
E
E
S
N
K
A
L
H
A
L
Sea Urchin
Strong. purpuratus
XP_781524
752
81324
E472
E
V
L
H
S
L
V
E
E
A
L
E
M
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P54888
726
78853
E473
G
L
V
T
S
R
E
E
I
P
D
L
L
K
L
Baker's Yeast
Sacchar. cerevisiae
P54885
456
49722
V203
D
E
Y
I
D
L
V
V
P
R
G
S
N
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.9
97.4
97.1
N.A.
95.3
95.2
N.A.
71.6
N.A.
84.4
82.1
N.A.
55.9
54.7
52.5
56.4
Protein Similarity:
100
94.9
98.2
98.6
N.A.
97.7
97.4
N.A.
74.9
N.A.
90.8
91.5
N.A.
70.8
69.5
69.5
73.3
P-Site Identity:
100
100
100
93.3
N.A.
100
93.3
N.A.
6.6
N.A.
60
80
N.A.
73.3
20
66.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
13.3
N.A.
93.3
93.3
N.A.
80
46.6
73.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.6
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.1
38.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
74
47
0
7
0
7
14
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
7
0
0
0
7
0
0
0
0
7
7
0
0
0
14
% D
% Glu:
7
7
0
67
0
14
20
14
14
0
0
7
0
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
80
67
0
7
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
7
0
0
47
0
0
0
0
0
54
7
0
% H
% Ile:
0
0
0
7
0
0
0
0
14
0
54
7
0
0
0
% I
% Lys:
0
0
67
0
0
0
0
0
0
14
0
0
0
7
0
% K
% Leu:
7
7
7
0
0
14
0
0
0
0
20
74
7
47
80
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
14
0
0
% M
% Asn:
0
0
7
0
0
0
20
0
67
0
0
0
7
0
0
% N
% Pro:
0
7
0
0
0
0
0
0
7
7
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
7
0
0
0
54
0
0
7
7
7
% R
% Ser:
0
0
0
0
14
7
0
54
0
7
0
7
7
0
0
% S
% Thr:
0
0
0
14
0
7
0
14
0
0
0
0
0
7
0
% T
% Val:
0
14
14
0
0
0
14
14
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _